DOCRU- TAB
November 30, 2017
MO-ZINE TAB
November 30, 2017

FEXMARE TAB

(FEXOFENADINE 120 MG + MONTELUKAST 10 MG)

SKU: 897d20b04e3d Categories: ,
Description

Packing: -10X10
M.R.P: – 1350
Drug Interactions of Montelukast 10mg + Fexofenadine 120mg: Metabolism May Be Increased With Rifampicin, Phenobarbital, Phenytoin. Peripheral Oedema May Occur With Prednisone. Contraindications of Montelukast 10mg + Fexofenadine 120mg: NA Mechanism of Action of Montelukast 10mg + Fexofenadine 120mg: Montelukast Is A Selective Leukotriene Receptor Antagonist That Blocks The Effects Of Cysteinyl Leukotrienes In The Airways. Absorption: Rapidly Absorbed From The GI Tract (Oral). Peak Plasma Concentrations In 2-4 Hr. Mean Oral Bioavailability: 64%. Distribution: Protein-Binding: >99%. Metabolism: Extensively Hepatic By CYP3A4, CYP2A6 And CYP2C9 Isoenzymes. Excretion: Principally Via Faeces; Elimination Half-Life Prolonged In Mild To Moderate Hepatic Impairment. Special Precautions for Montelukast 10mg + Fexofenadine 120mg: Not For The Relief Of Acute Bronchospasm. Not To Be Used As Monotherapy For The Prevention Of Exercise-Induced Bronchospasm. Patients In Whom Asthma Is Precipitated By Aspirin Or Other NSAIDs Should Continue To Avoid Aspirin And NSAIDs. Do Not Abruptly Substitute For Oral Or Inhaled Corticosteroids. Be Alert For Any Signs Of Churg-Strauss Syndrome. Pregnancy And Lactation. Children <6 Mth.

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