PREGSMART-200 INJECTION
May 15, 2018
SIGMERO-1000
May 15, 2018

RION-375

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Description

COMPOSITION: – AMOXYCILLIN TRIHYDRATE 250 MG+ CLAVULANIC ACID 125 MG

PACKING: – 10X1X10

M.R.P: -1500

Amoxycillin has a broad spectrum of bacteria it treats a wide variety as this medication is a semi synthetic derivative of penicillin. Its main function is to inhibit the formation of bacterial cell wall.

Clavulanic acid functions by preventing certain bacteria`s to become resistant to amoxicillin. Also, in combination to Amoxycillin an extended anti-bacterial spectrum is observed which prolongs its effects.

PHARMACOLOGY

PHARMACOKINETICS:

  • ABSORPTION: A good rate of absorption was found when administered orally. Parenteral absorption was also found.
  • DISTRIBUTION: Amoxycillin does not cross the blood brain barrier and diffuses into most of the body tissues readily. There is presence of potassium in traces which help in binding to proteins.
  • METABOLISM AND EXCRETION: Upto 70% of amoxicillin and 40% of Clavulanic acid is excreted unchanged through the urine that too after first 6 hours of its administration.

Indications and Usage:

  • Infection of upper and lower tract.
  • For middle ear inflammation
  • Acute Sinusitis.
  • Acute exacerbation of chronic bronchitis.
  • And Pneumonia.
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