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SPADSPAS

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Description

Product Name: SPADSPAS

COMPOSITION: DROTAVERINE 80 MG + MEFENAMIC ACID 250 MG

PACKING: – 10X10

M.R.P: – 750

Drotaverine is an effective spasmolytic drug.

SPADSPAS (DROTAVERINE 80 MG + MEFENAMIC ACID 250 MG) is used to treat spasms in biliary tract, spasm in the urinary tract, gastrointestinal spasm and primary dysmenorrhea.

Pharmacology

Pharmacodynamics: –

Drotaverine exerts its action by prohibiting phosphoesterase enzyme these results in the decrease in calcium ions as well as cyclic AMP. This decreased level of calcium uptake changes the distribution of calcium among the cells and will dilate the unstiped muscles and other blood vessels to relieve them from the spasms.

Another drug molecule, Mefenamic Acid, which is a NSAID inhibits the pain mediators and delays the formation of prostaglandins and prevents their release at the site of injury. This helps in relieving from pain.

Pharmacokinetics of SPADSPAS

  • Absorption: Quick absorption was observed after oral administration.
  • Distribution: Widely distributed as protein bound.
  • Metabolism: Metabolism takes place in the liver.
  • Excretion: Excretion of the drug is associated with bile.

INDICATIONS

  • Muscle Spasm 
  • Colic Pain 
  • Dysmenorrhoea 
  • Post Surgical Spasm 
  • Irritable Bowel Syndrome 
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