ZIMFE P
November 30, 2017
SIGMERO-T
November 30, 2017

PAFRE INJ

(DICLOFENAC SODIUM INJ(1ML)

Description

Packing: – 1ML
M.R.P:- 15
Pharmacology
Pharmacokinetics
Diclofenac Sodium
• Absorption: – Diclofenac is NSAIDs with anti-inflammatory, analgesic and antipyretic properties. It is rapidly and almost completely absorbed when administered as an oral dose. Food does not have a significant effect on the extent of oral absorption.
• Protein Binding: -At therapeutic concentrations it is more than 99% bound to plasma proteins. Metabolism: -Diclofenac and/or its metabolites are rapidly and preferentially taken up and retained in inflamed tissues. It penetrates synovial fluid where concentrations may persist even when plasma concentrations fall.
• Half-Life: – The terminal half-life is about 1 to 2 hours. Diclofenac acts by inhibiting cyclooxygenase, thus prevents the formation of prostaglandins, the mediators of inflammation. It also inhibits lipoxygenase thus preventing the synthesis of leukotrienes. Thus it acts on both the pathways and is a very potent anti-inflammatory drug/ medicine.

Additional information
Pack Size

Download Product List
Contact Us
close slider