(ONDENSETRON 4 MG – MOUTH DISSOLVING)
BRAND NAME :- EMDAR
COMPOSITION :- ONDANSTERON tablet
MEDICATION USED FOR
Ondansetron used to prevent nausea and vomiting that may be caused by surgery cancer . Chemotherapy or radiation treatment . Ondansetron an anti- sickness medicines ( sometimes called an antimetic ) that is mainly used to help with nausea and vomiting . Ondansetron also used to prevent and treat feelings of sickness and vomiting caused by chemotherapy , radiotherapy and after surgery . Ondansetron the action of chemicals in thebody that can trigger nausea and vomiting . Ondansteron can treat nausea and vomiting after surgery . Ondansetron to treat nausea and vomiting caused by cancer treatment such as chemotherapy and radiation therapy . Ondansetron may also help prevent the common complication of shivering in people who have had anthesia . Ondansteron belongs to a class of drugs called serotonin also called antiemetics , meaning they block nausea and vomiting . Ondansetron also useful in gastroenteritis . Ondansetron used to treat morning sickness and hypermesis gravidarum of pregnancy.
MECHANISM OF ACTION
Ondansetron works by blocking the action of serotonin , a natural substance that may cause nausea and vomiting . Ondansetron a selective antagonist of the serotonin receptor subtype , 5-HT3 . Cytotoxic chemotherapy are associated with the release of serotonin from enterochromaffin cells of the small intestine. Presumably initiating a vomiting reflax through stimulation of 5-HT3 receptor located on vagal afferents. Ondansetron may block the initiation of this reflax. Ondansetron and the other members of the setron drug family are serotonin antagonists. . This means these drug blocks the serotonin receptor in the chemoreceptor trigger zone ( CTZ) within the medulla oblongata . The chemoreceptor trigger zone ( CTZ) communicates with the vomiting centre to imitiate vomiting . By blocking the serotonin receptor , there`s less serotonin that enters the chemoreceptor trigger zone (CTZ) , which decreases communication with the vomiting centre . Ultimately , the patients experiences reduced nausea and vomiting .