M.R.P: – 890
Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease whereas Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. Pantoprazole acts by selectively inhibiting the H+/K+-ATPase enzyme in the secretory canaliculus of the stimulated parietal cell. Domperidone stimulates GI activity by acting as a competitive antagonist at dopamine D2-receptors.
Pharmacokinetics: – 1. Pantoprazole:
Bioavailability: – The absolute bioavailability from the tablet was found to be about 77 %.
2. Domperidone: Domperidone acts as a gastrointestinal emptying (delayed) adjunct and peristaltic stimulant. The gastroprokinetic properties of Domperidone are related to its peripheral dopamine receptor blocking properties.
Indications: Antacids Antireflux Agents & Antiulcerants / GIT Regulators, Antiflatulents Anti-Inflammatories
The composition of Pantoprazole & Domperidone Capsule is helpful for gastroesophageal reflux disease (GERD), heartburn due to hyperacidity, inflammation of the food pipe, and peptic ulcer. The person suffering from the problem of indigestion can take the help of this medication. The medication helps in providing relief from stomach pain. The excessive amount of stomach acid is prevented with the help of this medication. The person also gets relief from the vomiting, nausea, etc. the stomach acid is reduced with the help of this medication. The person gets relief from the stomach-related issues and is able to improve his indigestion.
The best time considered to take the tablet is at least an hour before the meal. It is considered best to swallow the whole tablet with a glass of water. The intake of the tablet should not be administered own as the intake of the tablet is based on the medical condition of the person.
There are some common side effects that can occur after the intake of the tablet. Although these side effects disappear on their own and do not cause any negative effects. The common side effects which occur after the intake of the medication are as follows :
During the treatment, some people require precautions to consider. The precautions are as follows :
It is not considered safe for the person to drive the vehicle during the treatment. If the person is physically stable and mentally focussed, then only he is advised to drive the vehicle or to do the work that needs concentration.
No, it is not considered safe to consume alcohol while undergoing the treatment.
PANTOPRAZOLE 40 MG & DOMPERIDONE 30 MG