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Ondansetron Hydrochloride Oral Solution-Manufacturers, Supplier, Third Party Contract Manufacturing & PCD Pharma Franchise

Ondansetron Hydrochloride Oral Solution


Ondansetron Hydrochloride Oral Solution is used to prevent nausea and vomiting that may be caused by surgery cancer. Chemotherapy or radiation treatment. Ondansetron anti-sickness medicines ( sometimes called an antiemetic ) are mainly used to help with nausea and vomiting.

Ondansetron is also used to prevent and treat feelings of sickness and vomiting caused by chemotherapy, radiotherapy, and after surgery. Ondansetron is the action of chemicals in the body that can trigger nausea and vomiting. Ondansetron can treat nausea and vomiting after surgery.Ondansetron to treat nausea and vomiting caused by cancer treatment such as chemotherapy and radiation therapy.

Ondansetron may also help prevent the common complication of shivering in people who have had anesthesia. Ondansteron belongs to a class of drugs called serotonin also called antiemetics, meaning they block nausea and vomiting. Ondansetron is also useful in gastroenteritis. Ondansetron is used to treat morning sickness and hypermesis  gravidarum of pregnancy.


Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Ondansetron is a selective antagonist of the serotonin receptor subtype, 5-HT3. Cytotoxic chemotherapy is associated with the release of serotonin from enterochromaffin cells of the small intestine.

Presumably initiating vomiting reflux through stimulation of 5-HT3  receptor located on vagal afferents. Ondansetron may block the initiation of this reflux. Ondansetron and the other members of the strong drug family are serotonin antagonists. . Which means these drug blocks the serotonin receptor in the chemoreceptor trigger zone ( CTZ) within the medulla oblongata.

The chemoreceptor trigger zone ( CTZ)  communicates with the vomiting center to initiate vomiting. By blocking the serotonin receptor, there`s less serotonin that enters the chemoreceptor trigger zone (CTZ),  which decreases communication with the vomiting center. Ultimately, the patients experience reduced nausea and vomiting.

Directions For Use

To take the medication in the exact dose the person is advised to measure the solution with the measuring cup. Taking the medication in the exact dose help the person in treating his problem. Based on the medical condition the person is suggested the dose by the doctor. 

Side Effects Of Ondansetron Hydrochloride Oral Solution

Unlike the other medication the composition of this suspension also affects the health of the person for a short duration with the following side effects :

  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Fatigue

Precautions To Be Taken

Following are some of the cautions that should be taken care of during the treatment of this medication :

  • Before the use of the medication, the person is advised to inform the doctor if the person is sensitive to any of the components or the supplements. 
  • If the person is suffering from osteoporosis or any bone problem then he is advised to inform the doctor before the use of the medication. 
  • Before the use of the medication, the woman is advised to inform the doctor if she is pregnant or breastfeeding. 

Frequently Asked Questions (FAQs)

  1. What kind of diet is to be avoided during the intake of Ondansetron Hydrochloride Oral Solution?

While undergoing the treatment of the medication the person is advised to avoid the intake of caffeinated drinks, alcohol, fatty food, etc to avoid gastrointestinal problems.

  1. Can the use of the medication cause dehydration?

Yes, the medication can cause dehydration. It is advised to drink plenty of water at regular intervals to prevent dehydration. 


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